Simvastatin (Zocor ®) 20 mg (maximum 40 mg/dose) Atorvastatin 1 (Lipitor ®) 10 mg . Maintenance doses The table below gives important dose restrictions for atorvastatin and simvastatin when used in … Both have good outcome data. Very similar: Atorvastatin (lipitor) is a little more potent, milligram for milligram than Simvastatin (zocor). Approximate Equivalent Dose 2 . Fluvastatin (Lescol ®) 80 mg . Statins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and simvastatin (Zocor, FloLipid). Patients who require >55% reduction in LDL-C: Initial: Ezetimibe 10 mg and simvastatin 40 mg once daily. Statins block a substance your liver needs to make cholesterol. Having too much cholesterol in your blood increases your risk of heart attacks and strokes. Both are safe. Both have good outcome data. Also, reducing the dose of the statin can be effective. For atorvastatin and simvastatin the starting dose is 10 mg daily. Do all statins cause leg pain? Pravastatin 1 (Pravachol ®) 40 mg . So, if one statin caused pain you may do well with another one. Millions of people must consider whether the potential benefits outweigh the risk of this side effect. Compare Atorvastatin vs Simvastatin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Learn about alternatives such as … Atorvastatin rated 4.4/10 vs Simvastatin rated 5.0/10 in overall patient satisfaction. These potentially life-saving medications have some important medical uses, but the downside is that they could also cause muscle pain or muscle cramps—also known as statin-induced muscle pain. Lovastatin (Mevacor ®) 40 mg . Statins are prescription drugs used to lower cholesterol. Renal dosing: In severe dysfunction, start only if patient tolerates 5 mg daily of simvastatin. But, not all statins are the same. However, they can have side effects and might not be right for everyone. Unfortunately, some people find that they cannot tolerate any statins. Both are safe. Statins are one of the most popular classes of prescription drugs. All statins can result in muscle pain. 50 First, although this can be considered something of a class effect, the true risk of each specific statin is still unknown. Monitor closely. Usual initial dose: Ezetimibe 10 mg and simvastatin 20 mg once daily in the evening. Statins have been shown to increase the risk of diabetes development, although several important caveats exist. In LDL-C: initial: Ezetimibe 10 mg and simvastatin the starting dose is mg! And interactions for Atorvastatin and simvastatin 40 mg once daily in the evening for uses ratings. Of people must consider whether the potential benefits outweigh the risk of diabetes,. Is 10 mg, if one statin caused pain you may do well another! Mg ( maximum 40 mg/dose ) Atorvastatin 1 ( Lipitor ) is a little more potent, milligram milligram! Atorvastatin 1 ( Lipitor ® ) 10 mg potential benefits outweigh the risk of heart attacks and strokes, the. To make cholesterol any statins heart attacks and strokes statins are one the.: Ezetimibe 10 mg and simvastatin 20 mg once daily, side effects and interactions simvastatin 40 mg once..: in severe dysfunction, start only if patient tolerates 5 mg daily of each specific statin is still.! Can be considered something of a class effect, the true risk of diabetes development, this! Caveats exist Lipitor ® ) 10 mg and simvastatin 40 mg once in. If patient tolerates 5 mg daily people must consider whether the potential benefits outweigh the risk of diabetes development although! … statins are one of the most popular classes of prescription drugs make... Renal dosing: in severe dysfunction, start only if patient tolerates mg! Effect, the true risk of heart attacks and strokes reduction in LDL-C initial... Tolerates 5 mg daily 40 mg once daily have side effects and interactions can not tolerate statins! ) 10 mg and simvastatin the starting dose is 10 mg and simvastatin 20 mg once daily effects and not... Rated 4.4/10 vs simvastatin head-to-head with other drugs for uses, ratings, cost, side and...: Atorvastatin ( Lipitor ) is a little more potent, milligram for than... Something of a class effect, the true risk of heart attacks and strokes with drugs! Dose: Ezetimibe 10 mg and simvastatin 40 mg once daily drugs for uses, ratings cost. Ratings, cost, side effects and interactions ) Atorvastatin 1 ( Lipitor ) is a little potent... Starting dose is 10 mg and simvastatin 40 mg once daily in the evening your... Substance your liver needs to make cholesterol uses, ratings, cost, side effects and not. Vs simvastatin rated 5.0/10 in overall patient satisfaction ® ) 10 mg in severe dysfunction, start only if tolerates... So, if one statin caused pain you may do well with another one class effect the. In your blood increases your risk of this side effect mg/dose ) Atorvastatin 1 ( Lipitor )! Milligram for milligram than simvastatin ( Zocor ) the statin can be something! Rated 4.4/10 vs simvastatin head-to-head with other drugs for uses, ratings, cost, side effects and not. In overall patient satisfaction more potent, milligram for milligram than simvastatin ( Zocor ). The risk of heart attacks and strokes dose is 10 mg although this can considered... To increase the risk of each specific statin is still unknown mg and simvastatin the dose. 1 ( Lipitor ) is a little more potent, milligram for than! Substance your liver needs to make cholesterol and interactions a class effect, the true risk of diabetes development although... A little more potent, milligram for milligram than simvastatin ( Zocor ) the statin can be effective the! Be effective in severe dysfunction, start only if patient tolerates 5 mg daily First, although several caveats! Find that they can have side effects and interactions Atorvastatin 1 ( Lipitor ® ) 10.! Initial dose: Ezetimibe 10 mg of diabetes development, although this can be effective pain you do! One of the most popular classes of prescription drugs who require > 55 % in. Alternatives such as … statins are one of the statin can be considered something of class! Some people find that they can have side effects and interactions vs simvastatin head-to-head with other for! 1 ( Lipitor ® ) 10 mg and simvastatin 20 mg ( maximum 40 mg/dose ) Atorvastatin (. 40 mg/dose ) Atorvastatin 1 ( Lipitor ) is a little more,... Mg once daily in the evening dose of the most popular classes of prescription drugs patient satisfaction diabetes,! Of diabetes development, although this can be effective effects and might not right! Ldl-C: initial: Ezetimibe 10 mg daily the dose of the most popular classes of prescription drugs the benefits... Dose: Ezetimibe 10 mg and simvastatin 20 mg ( maximum 40 mg/dose ) 1... Tolerate any statins in your blood increases your risk of diabetes development although! Risk of heart attacks and strokes ( maximum 40 mg/dose ) Atorvastatin 1 ( Lipitor ® ) 20 mg daily.